荷蘭HyCult Biotechnology(HBT)  www.hbt.nl
荷蘭HyCult Biotechnology(HBT)位于荷蘭，主要側(cè)重與病理學(xué)診斷有關(guān)的全套產(chǎn)品研發(fā)，既有純化的重組蛋白和多肽，也有單抗和多抗，還開(kāi)發(fā)了相應(yīng)的診斷ELISA試劑盒。近年來(lái)，HBT還開(kāi)發(fā)了全世界獨(dú)有的與心血管系統(tǒng)疾病相關(guān)的診斷試劑（如動(dòng)脈粥樣硬化蛋白C抗凝集途徑、JAM-A內(nèi)皮細(xì)胞途徑）；磷脂氧化途徑檢測(cè)；TNF各亞型及各個(gè)受體全套產(chǎn)品；組織損傷標(biāo)志物－FABP相關(guān)產(chǎn)品（如檢測(cè)心臟、肝臟和小腸細(xì)胞損傷時(shí)出現(xiàn)的FABP）；細(xì)胞損傷檢測(cè)－FABP；內(nèi)毒素和其它微生物毒素的檢測(cè)（內(nèi)毒素抗體、內(nèi)毒素阻斷試劑、人BPI防御素、LBP和SLPI的抗體和ELISA試劑盒）。
 Hycult biotechnology b.v., also known as Hbt, produces recombinant proteins, monoclonal and polyclonal antibodies and ELISA kits for immunology and cell biology research.

Hbt products are manufactured and supplied according to ISO9001-2000 guidelines. The ISO certificate has been obtained for development, manufacturing and delivery of test kits, proteins, monoclonal and polyclonal antibodies in the field of microbial toxis, innate immunity, cell biology, toxicology and inflammatory mediators.

Main products are antibodies and assays for research of neutrophil proteins/antimicrobial peptides (Defensin, MPO, Calprotectin); early cell- and tissue damage (FABP); complement and collectins (MBL/MASP-2 and related proteins); vascular/oxidation damage (JAM, VAP-1, Nitrotyrosine); endotoxin & other microbial toxins, coagulation and Toll-like receptors.
Hbt Research
Hbt's aim in research is developing antibodies and assays that fulfill the need and demand of the research community. Products are being developed and commercialized in full cooperation with European, US, Japanese and Australian universities and research institutes.
Our program currently involves the development of reagents such as:

* Several Fatty Acid Binding Proteins (A-FABP and B-FABP) that happen to be excellent new and versatile markers for specific cell- and tissue damage detection
* Antibodies and assays for Collectin research (L-Ficolin, H-Ficolin, MASP-3, SP-A and SP-D).
* Neutrophil proteins / antimicrobial peptides (antibodies and assays for nGAL and beta-defensins)
* Assays for oxidative stress (MPO for various species such as rat, bovine and equine)
* Antibodies and assays for vascular research (ADAMTS13, ZO-1, JAM-A)
* Specific markers for intestinal diseases (sMAdCAM-1, I-LBP/IL-FABP)
* Neurological markers (brain alpha-dystroglycan, CCK1R, CCK2R)